News & Events | Westlake Laboratory

NEWS & EVENTS

News

News

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WeKwikGene Plasmid Repository – Plasmids of the year!

2025-06-05

WeKwikGene is proud to celebrate its first year of successful operation.

Researchers Discover that Donut-shaped Mitochondria Lead to Taller Children

2023-09-14

Prof. Lianfeng Wu, Prof. Xianjue Ma, and Prof. Jian Yang from Westlake Laboratory recently published an article in the journal of Cell Research entitled "Maternal Aging Increases Offspring Adult Body Size via Transmission of Donut-Shaped Mitochondria".

Reproductive Biology Breakthrough Reported in Cell by Jianping Wu’s Group

2023-06-20

Prof. Jianping Wu’s group published on June 8 a Cell paper reporting on their study of the structures of mouse and human sperm flagellar doublet microtubules (DMTs). The study identified a new type of male infertility, which has been named MIP-variant-associated asthenozoospermia (MIVA) and represents a breakthrough in reproductive biology that will undoubtedly contribute to future diagnosis and treatment of male infertility.

Four Days, 130 Presentations: Westlake Laboratory Co-hosts CBIS 2022

2022-11-29

On December 19-22, Westlake University and the Chinese Biological Investigators Society ("CBIS") will jointly launch an "academic marathon" - the 13th Chinese Biological Investigators Society 2022 biennial meeting.

Evidence in Mice That Bacteria in Tumors Help Cancer Cells Metastasize

2022-04-08

Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report April 7 in the journal Cell.

Scientific Progress

Scientific Progress

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07月24日周四

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On the quest for the fluorescent “superheroes” 2024-02-26

Prof. Kiryl Piatkevch's research team at Westlake laboratory, in collaboration with Fedor Subach, reported a new extremely stable and bright green fluorescent protein, mBaoJin, which is suitable for super-resolution long-term live cell imaging and expansion microscopy.

Researchers Discover that Donut-shaped Mitochondria Lead to Taller Children 2023-09-14

Prof. Lianfeng Wu, Prof. Xianjue Ma, and Prof. Jian Yang at Westlake Laboratory recently published an article in the journal of Cell Research entitled "Maternal Aging Increases Offspring Adult Body Size via Transmission of Donut-Shaped Mitochondria". Their study investigated nematodes, fruit flies, and humans, and found that, in all three, the reproductive age of a mother can affect the height and other characteristics of her children even when they reach adulthood. The research team set out to discover the biological mechanism responsible for this phenomenon.

MeDuSA: a novel method for investigating cellular state dynamics in tissue-level transcriptomic data 2023-07-14

On July 13, 2023, Nature Computational Science published online a research study led by Liyang Song, a doctoral student from Prof. Jian Yang’s lab at Westlake Laboratory, titled “Mixed model-based deconvolution of cell-state abundances (MeDuSA) along a one-dimensional trajectory". This study developed a method named MeDuSA to estimate the abundances of cells at different states in tissue-level transcriptomic data. The research team applied this method to various diseases including human cancers and COVID-19, successfully identifying cell states related to disease onset, development, prognosis, and drug treatment responses. This work significantly enhances our understanding of cell state dynamics in different biological processes.

Searching for disease genes with OPERA 2023-06-20

On June 19, 2023, Cell Genomics published an online research paper titled “Joint analysis of GWAS and multi-omics QTL summary statistics reveals a large fraction of GWAS signals shared with molecular phenotypes”. This study developed a method called OPERA that efficiently integrates and analyzes large-scale genomic and multi-omics data from human populations. This method is aimed at mapping human complex disease-related genes and genomic functional regions at a finer resolution, ultimately enhancing our understanding of the genetic regulatory mechanisms involved in complex diseases.

Cell Reports Reproductive Biology Breakthrough by Prof. Jianping Wu's Group 2023-06-20

Prof. Jianping Wu’s group from the School of Life Sciences at Westlake University published on June 8 a Cell paper reporting on their study of the structures of mouse and human sperm flagellar doublet microtubules (DMTs). The study identified a new type of male infertility, which has been named MIP-variant-associated asthenozoospermia (MIVA) and represents a breakthrough in reproductive biology that will undoubtedly contribute to future diagnosis and treatment of male infertility.

Westlake's Prof. Zhen Yan’s Research Team Publishes Article Online on Cell 2023-01-10

Prof. Zhen Yan’s research team at Westlake published an article online on Cell (https://doi.org/10.1016/j.cell.2022.10.030) entitled "Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes".

Academic Reports

Academic Reports

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DNA Repair / Gene Maintenance: Westlake x Science Joint Online Symposium #10

2024-11-25

On November 22, 2024, over 150,000 viewers from around the world attended this year’s final part of our live, online symposium series, jointly organized by Science/AAAS and Westlake University, titled “DNA Repair / Gene Maintenance.”

Aging and Neurodegeneration: Westlake x Science Joint Online Symposium #9

2024-10-25

On October 24, 2024, Westlake Laboratory and Westlake University, in collaboration with Science/AAAS, successfully held the ninth online symposium titled "Aging and Neurodegeneration."

Protein Therapeutics: Westlake x Science Joint Online Symposium #8

2024-09-26

On September 24th, 2024, over 23,100 viewers from around the world enjoyed the eighth part of our live, online symposium series, "Protein Therapeutics," jointly organized by Science/AAAS, Westlake Laboratory and Westlake University.

Gene and Cell Therapy: Westlake x Science Joint Online Symposium #7

2024-08-01

Gene and cell therapy is a set of biological techniques that aim to treat or prevent diseases by modifying genes or cells, and which are at the forefront of modern medicine. On July 24th, 2024, the 7th Westlake University-Science/AAAS joint online symposium, titled “Gene and Cell Therapy" was enjoyed by over 84,900 viewers from around the world.

Synthetic Biology: Westlake x Science Joint Online Symposium 2024 #6

2024-07-01

On June 25, 2024, the sixth Westlake University-Science/AAAS joint online symposium, “Synthetic Biology" captivated a global audience, featuring three distinguished speakers at the forefront of synthetic biology. Organized by Science/AAAS and Westlake University, this event provided a deep dive into the latest advancements and applications in the field of synthetic biology.

Notice

Notices

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JUN. 11

SYMPOSIUM 04 | Lipid metabolism in health and disease

In this webinar, we will explore the crosstalk between lipid metabolism and multiple diseases including obesity, cardiorenal metabolic syndrome, thrombosis, and cancer, and discuss perspectives on how to leverage lipid-targeting strategies to benefit human health.

MAY. 14

SYMPOSIUM 03 | Cancer immunotherapy - accomplishments and future

In this webinar, we will explore recent achievements in cancer immunotherapy, particularly in adoptive cell therapies.

APR. 15

SYMPOSIUM 02 | The evolving epigenome-functions and applications

In this webinar, we will explore how epigenetic modifications establish and maintain cell identity, as well as how their evolving patterns can be harnessed to reconstruct the body's biological history.

MAR. 06

SYMPOSIUM 01 | Mitochondria in health and disease

This webinar delves into the molecular frontiers of mitochondrial biology, bridging technological innovations with mechanistic breakthroughs to address longstanding questions in the field.

NOV. 07

SYMPOSIUM 10 | DNA repair / Genome maintenance

Our speakers will explore the complex interplay between genome instability and DNA repair, highlighting innovative therapeutic strategies and interventions that could revolutionize the treatment of genetic disorders and cancers.